Human antibody libraries for therapeutic antibody discovery should maximize the probability of obtaining specific, high affinity and developable antibodies. ALTHEA Gold Libraries™ meet these demands and are being successfully used by several academic and biotech companies.
Humanization methods should increase the human content of therapeutic antibody to minimize immunogenic reactions, retain potency to minimize costs in further engineering processes, and secure intellectual property. GlobalBio’s Humanization Method (GBM) Humanization™ meets these goals and has been applied to engineer over a dozen of antibodies from several academic and biotech companies.
Therapeutic antibodies should meet high functional and development standards to be successful in preclinical and clinical development. Based on bioinformatics and modeling tools, compounded with more that twenty years of experience in the field, we engineer antibody-based therapeutics to accomplish such high standards.